Bacteria in humans, food and animals continue to show resistance to the most widely used antimicrobials, says the latest report on antimicrobial resistance in zoonotic bacteria in Europe.

Scientists warn that resistance to ciprofloxacin, an antimicrobial that is critically important for the treatment of human infections, is very high in campylobacter, thus reducing the options for effective treatment of severe foodborne infections. Multi-drug resistant salmonella bacteria also continues to spread across Europe.

The findings of this latest annual Europe-wide report by EFSA and the European Centre for Disease Prevention and Control (ECDC) underline again that antimicrobial resistance poses a serious risk to human and animal health. This risk was identified by the Commission as a major priority in its political agenda on food safety.

Vytenis Andriukaitis, EU Commissioner for Health and Food Safety, said; “Every year in the EU, infections caused by antimicrobial resistance lead to about 25,000 deaths – but the threat is not confined to Europe. This is a global problem that requires a global solution.

“The EU has long been at the forefront in the fight against antimicrobial resistance and is a leader in the field. Our agencies EFSA and ECDC, by combining their expertise in human and animal health, are putting together many of the pieces in this complex puzzle and providing policy makers the world over with valuable scientific advice.”

The report also found evidence of resistance to the antimicrobial colistin in salmonella and E. coli among poultry in the EU. Mike Catchpole, Chief Scientist for ECDC, said; “This is worrying because it means that this last-resort drug may soon no longer be effective for treating severe human infections with salmonella.”

In addition to the high levels of resistance shown throughout Europe, the report found that there are significant regional differences. The highest levels of antimicrobial resistance (AMR) are observed in eastern and southern Europe. Marta Hugas, Head of EFSA’s Biological Hazards and Contaminants unit, said; “In northern Europe, there is lower resistance in bacteria from poultry, particularly in countries with low use of antimicrobials in animals.”